{
  "resourceType": "DiagnosticReport",
  "id": "22fd4d37-6dd2-4b81-a746-4907c6de4f9c",
  "meta": {
    "profile": [
      "http://hl7.org/fhir/StructureDefinition/DiagnosticReport"
    ],
    "versionId": "1.0",
    "lastUpdated": "2026-11-01T01:07:56Z"
  },
  "status": "final",
  "category": [
    {
      "coding": [
        {
          "system": "http://terminology.hl7.org/CodeSystem/v2-0074",
          "code": "RAD",
          "display": "Radiology & Clinical Neurology"
        }
      ]
    }
  ],
  "code": {
    "coding": [
      {
        "system": "http://loinc.org",
        "code": "81247-9",
        "display": "Master Diagnostic Radiology and Neurology Consensus Report"
      }
    ],
    "text": "NeuroAI Multimodal Consensus Protocol"
  },
  "subject": {
    "reference": "Patient/PAT-001",
    "display": "Patient identifier PAT-001"
  },
  "effectiveDateTime": "2026-11-01T01:07:56Z",
  "issued": "2026-11-01T01:07:56Z",
  "performer": [
    {
      "display": "NeuroAI Clinical Desktop Workstation (Certified Decision Support System)"
    }
  ],
  "result": [
    {
      "reference": "#obs-edss_score-f0e2c4"
    },
    {
      "reference": "#obs-n_wbv-4cd715"
    },
    {
      "reference": "#obs-hippocampus_vol-2ccfd9"
    },
    {
      "reference": "#obs-ventricles_vol-9c863d"
    },
    {
      "reference": "#obs-t2_lesions_count-09fc68"
    },
    {
      "reference": "#obs-serum_nfl_pg_ml-b02bca"
    },
    {
      "reference": "#obs-conformal-06049e"
    }
  ],
  "contained": [
    {
      "resourceType": "Observation",
      "id": "obs-edss_score-f0e2c4",
      "status": "final",
      "code": {
        "coding": [
          {
            "system": "http://loinc.org",
            "code": "77402-6",
            "display": "Expanded Disability Status Scale score"
          }
        ],
        "text": "Expanded Disability Status Scale score"
      },
      "subject": {
        "reference": "Patient/PAT-001"
      },
      "effectiveDateTime": "2026-11-01T01:07:56Z",
      "valueQuantity": {
        "value": 2.5,
        "unit": "{score}",
        "system": "http://unitsofmeasure.org"
      }
    },
    {
      "resourceType": "Observation",
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      "status": "final",
      "code": {
        "coding": [
          {
            "system": "http://loinc.org",
            "code": "96568-1",
            "display": "Normalized whole brain volume ratio"
          }
        ],
        "text": "Normalized whole brain volume ratio"
      },
      "subject": {
        "reference": "Patient/PAT-001"
      },
      "effectiveDateTime": "2026-11-01T01:07:56Z",
      "valueQuantity": {
        "value": 0.77,
        "unit": "ratio",
        "system": "http://unitsofmeasure.org"
      }
    },
    {
      "resourceType": "Observation",
      "id": "obs-hippocampus_vol-2ccfd9",
      "status": "final",
      "code": {
        "coding": [
          {
            "system": "http://loinc.org",
            "code": "96570-7",
            "display": "Hippocampal volume"
          }
        ],
        "text": "Hippocampal volume"
      },
      "subject": {
        "reference": "Patient/PAT-001"
      },
      "effectiveDateTime": "2026-11-01T01:07:56Z",
      "valueQuantity": {
        "value": 3900.0,
        "unit": "mm3",
        "system": "http://unitsofmeasure.org"
      }
    },
    {
      "resourceType": "Observation",
      "id": "obs-ventricles_vol-9c863d",
      "status": "final",
      "code": {
        "coding": [
          {
            "system": "http://loinc.org",
            "code": "96569-9",
            "display": "Lateral ventricular volume"
          }
        ],
        "text": "Lateral ventricular volume"
      },
      "subject": {
        "reference": "Patient/PAT-001"
      },
      "effectiveDateTime": "2026-11-01T01:07:56Z",
      "valueQuantity": {
        "value": 24000.0,
        "unit": "mm3",
        "system": "http://unitsofmeasure.org"
      }
    },
    {
      "resourceType": "Observation",
      "id": "obs-t2_lesions_count-09fc68",
      "status": "final",
      "code": {
        "coding": [
          {
            "system": "http://loinc.org",
            "code": "96571-5",
            "display": "Number of T2 demyelinating lesions"
          }
        ],
        "text": "Number of T2 demyelinating lesions"
      },
      "subject": {
        "reference": "Patient/PAT-001"
      },
      "effectiveDateTime": "2026-11-01T01:07:56Z",
      "valueQuantity": {
        "value": 14.0,
        "unit": "{count}",
        "system": "http://unitsofmeasure.org"
      }
    },
    {
      "resourceType": "Observation",
      "id": "obs-serum_nfl_pg_ml-b02bca",
      "status": "final",
      "code": {
        "coding": [
          {
            "system": "http://loinc.org",
            "code": "98765-4",
            "display": "Neurofilament light chain in serum"
          }
        ],
        "text": "Neurofilament light chain in serum"
      },
      "subject": {
        "reference": "Patient/PAT-001"
      },
      "effectiveDateTime": "2026-11-01T01:07:56Z",
      "valueQuantity": {
        "value": 42.0,
        "unit": "pg/mL",
        "system": "http://unitsofmeasure.org"
      }
    },
    {
      "resourceType": "Observation",
      "id": "obs-conformal-06049e",
      "status": "final",
      "code": {
        "coding": [
          {
            "system": "http://neuroai.org/fhir/codes",
            "code": "conformal-coverage-set",
            "display": "Split-Conformal 95% Coverage Diagnostic Set"
          }
        ],
        "text": "Conformal Diagnostic Prediction Set"
      },
      "subject": {
        "reference": "Patient/PAT-001"
      },
      "effectiveDateTime": "2026-11-01T01:07:56Z",
      "component": [
        {
          "code": {
            "text": "Coverage Guarantee"
          },
          "valueString": "95%"
        },
        {
          "code": {
            "text": "Prediction Set"
          },
          "valueString": "Multiple_Sclerosis"
        },
        {
          "code": {
            "text": "Is Ambiguous"
          },
          "valueBoolean": false
        },
        {
          "code": {
            "text": "Clinical Recommendation"
          },
          "valueString": "Диагностическая определенность высокая."
        }
      ]
    }
  ],
  "conclusion": "Consensus diagnosis: Multiple_Sclerosis (Multiple sclerosis (disorder)) with 96.5% model probability. Category: Аутоиммунное демиелинизирующее заболевание. Conformal set: ['Multiple_Sclerosis'].",
  "conclusionCode": [
    {
      "coding": [
        {
          "system": "http://snomed.info/sct",
          "code": "24700007",
          "display": "Multiple sclerosis (disorder)"
        }
      ]
    }
  ]
}